Blood Chemistry Testing

Which Blood Test Is Right for You?

A plain-English guide to your options — from a 57-marker entry panel to a 180-marker Randox Signature investigation that suits clients who cannot easily get to a clinic.

Stephen Duncan FDN-P MSc | 37 years clinical experience

Blood chemistry is not a single test

When a client says "I've had my bloods done," it usually means a GP has run a basic panel — perhaps a full blood count and thyroid TSH. What they've received is a yes/no safety check, not a picture of how their system is actually performing. The question "are you normal?" and the question "how are you functioning?" have completely different answers.

The range of options available now — from 57 markers to 180, from a clinic draw to a home visit from a qualified phlebotomist — means there is a workable path for almost every client. Cost, mobility, time, and how much clinical depth is needed will determine which route makes sense.

What follows is my honest assessment of the main options I use and recommend, including how each one fits into the TDG Five-Test Programme.

What I'm looking for in a blood chemistry panel

My minimum threshold for clinical usefulness is a panel that covers: full blood count with differential, comprehensive metabolic panel, a full thyroid assessment beyond TSH alone, lipid chemistry with sub-fractions, iron studies, sex hormones, key vitamins and minerals, inflammatory markers, and relevant metabolic markers like HbA1c, fasting insulin, and homocysteine. Below that threshold, the picture has too many gaps to be clinically actionable.

Several of the options below meet that threshold in different ways. My default has shifted towards the Regenerus panels, chiefly because they can be drawn at home — for a large proportion of my clients that is the difference between testing happening and not happening. The choice still depends on the clinical picture, the budget, and what else is being run alongside. Note too that the 57-marker panel does not cover fasting insulin or homocysteine; the Functional Platinum panel does.

The Four Main Options

Compared honestly — cost, coverage, convenience, and clinical fit

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Regenerus 57-Marker Panel

Clinically targeted · Home draw available
£517all-in · £317 test + £55 draw + £145 interpretation

Regenerus Labs is a UK-based functional laboratory I have worked with for many years — I co-founded Omnos, which is now integrated with Regenerus. Their 57-marker blood chemistry panel covers the essential clinical territory without unnecessary duplication. The panel has been curated for functional clinical work: the markers are selected with interpretation in mind, not just coverage for coverage's sake.

One honest correction to an earlier version of this page: this panel does not include CRP, ESR, fasting insulin or homocysteine. If those are the markers your question needs, the Functional Platinum panel below is the right choice — or your GP will run CRP and ESR at no cost. What makes Regenerus particularly useful is that the panel can be requested alongside home phlebotomy, and their reporting integrates well with the other functional tests in the TDG Five-Test Programme. For clients who are also running DUTCH Plus, GI-MAP, and OAT, the Regenerus panel fits cleanly into that interpretive framework.

57 markers Full thyroid (TSH, T3, T4) Full lipid panel Iron studies HbA1c Sex hormones Thyroid antibodies Liver + kidney function Vitamin D B12 + folate

Strengths

  • Home draw compatible
  • Integrates with TDG programme
  • Strong functional orientation
  • Excellent reporting
  • The only panel here with the omega-3 index
  • Lowest-cost route into a full workup

Considerations

  • Narrower than the Platinum panels below
  • No ApoB or Lp(a) as standard
  • No CRP, ESR, fasting insulin or homocysteine
  • No immunoglobulins or calcium
Best for: Clients running the full TDG Five-Test Programme; clients who need home phlebotomy; presentations where the core markers will tell the story without requiring the full Signature panel depth.
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Regenerus Functional Platinum Panel

Inflammation, immune and metabolic depth · Home draw available
£625all-in · £425 test + £55 draw + £145 interpretation

Eighty-three markers, and the panel I would now choose first where the clinical question involves inflammation, immune function or metabolic health. It covers a broad chemistry screen and adds the markers the 57-panel omits — the ones that most often turn out to matter in a stubborn presentation.

It is £108 more than the 57-marker panel and covers twenty-six more markers, which makes it the best value per marker of the three. That is not by itself a reason to choose it. The two panels cover genuinely different ground, and more markers is no help if they are not the markers your question needed.

83 markers hs-CRP + ESR Immunoglobulins IgA, IgG, IgM Fasting insulin + C-peptide Homocysteine Calcium + phosphate Reverse T3 Total IgE Fibrinogen Full thyroid + antibodies

Strengths

  • Home draw compatible
  • Inflammatory and immune markers as standard
  • Proper insulin resistance assessment
  • Best value per marker of the three

Considerations

  • No sex hormone panel as standard — £95 add-on
  • No cortisol, PSA, zinc or omega-3 index
  • Some results returned in non-UK units
  • £108 more than the 57-marker panel
Best for: Recurrent infection or unexplained inflammation; metabolic questions where HbA1c alone is not enough; anyone whose previous panels came back "normal" without explaining the symptoms. Useful add-ons: testosterone with free testosterone and SHBG (£95), oestradiol with progesterone (£40), parathyroid hormone (£85).
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Regenerus Platinum Plus FX

On request · not a routine recommendation
£824all-in · £624 test + £55 draw + £145 interpretation

Eighty-seven markers — the Functional Platinum panel plus a small number of additions, principally active B12 (holotranscobalamin), serum selenium and serum copper. Active B12 measures the usable fraction rather than the total, which genuinely matters, because a total B12 can read high while the active portion is low.

I list this for completeness rather than as a recommendation. The £199 step up from the Functional Platinum panel buys four extra markers. For most people that money does more if it goes towards a second test in a different domain — stool, urinary organic acids, or hormones. Worth ordering when there is a specific reason to want those markers, and I will say so if there is.

87 markers Everything in Functional Platinum Active B12 Selenium Copper DHEA-S
Best for: A specific reason to want active B12, selenium or copper. Otherwise the Functional Platinum panel does the same job for £199 less.
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Randox Signature Panel

Widest marker coverage · clinic visit required · no longer my default
£598all-in · draw + 2 consultations + report

Randox Health is a Northern Irish diagnostics company, and their Signature panel — approximately 130 markers for the male panel, up to 180 for the female — remains the widest marker coverage available to non-medical practitioners at this price point. If breadth is what you want, nothing else here matches it.

An honest update: this is no longer my default recommendation. Two practical reasons, and neither is about the quality of the science. Individual markers have been intermittently unavailable for some time, which means a panel can come back with gaps you have already paid for. And it requires a fasted clinic visit, with limited Scottish locations — which for a large proportion of my clients is the difference between testing happening and not happening.

I still order it where the extra breadth genuinely answers the question, particularly for cardiovascular work where ApoB and Lp(a) matter. It is a good panel. It is no longer the one I reach for first.

The panel includes comprehensive thyroid (TSH, Free T3, Free T4, thyroid antibodies), full cardiovascular risk markers including ApoB and Lp(a), detailed metabolic markers, sex hormones, full haematology with differential, liver and kidney function, and a range of nutrients. Critically, it includes markers that most NHS GPs do not routinely request — such as fasting insulin, homocysteine, and GGT.

Up to 180 markers ApoB + Lp(a) Full thyroid panel Fasting insulin Homocysteine HbA1c Sex hormones Full iron studies Inflammatory markers Nutrient status

Strengths

  • Unmatched marker breadth
  • ApoB and Lp(a) as standard
  • Clinics in major UK cities
  • Results via app, fast turnaround
  • Faster turnaround than the Regenerus panels

Considerations

  • Requires clinic visit (fasted)
  • Not available for home draw
  • Fewer Scottish locations
  • Some markers intermittently unavailable
  • Appointment availability varies
Best for: Cardiovascular questions where ApoB and Lp(a) change the picture; clients who can travel to a clinic, want maximum breadth, and are not troubled by the possibility of an occasional missing marker.
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Bloods & Beyond — Home Phlebotomy

Home visit · Qualified phlebotomist · UK-wide
£55–£95phlebotomy fee

Bloods & Beyond is a private phlebotomy service offering qualified blood draw at home or at a location of the client's choosing. This is not a testing service in itself — it is a draw service, meaning the blood is taken by their phlebotomist and sent to a laboratory (typically Regenerus or another specified lab) for analysis. The fee covers the visit and draw, not the panel itself.

For a significant proportion of my clients, the ability to have blood taken at home is not a convenience — it is a necessity. Older clients, those with mobility limitations, autoimmune conditions that affect energy and travel capacity, parents with young children, and busy professionals who cannot take half a day to travel to a clinic all benefit enormously from home phlebotomy.

The cost varies by location and timing — weekday appointments are towards the lower end, evenings and weekends higher. Combined with the Regenerus 57-marker panel, the total cost remains competitive with or below many clinic-based alternatives.

Strengths

  • No travel required
  • Fasting draw at home is easier
  • Reduces barrier for mobility-limited clients
  • Qualified, registered phlebotomists
  • Early morning slots available

Considerations

  • Fee is in addition to lab costs
  • Requires coordination with lab request
  • Availability varies by postcode
Best for: Clients with mobility limitations; elderly clients; those managing fatigue-based conditions; parents of young children; time-poor professionals who cannot attend a clinic during working hours.
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Superdrug Online Doctor Blood Tests

Walk-in · High Street · Entry-level panels
£49–£149by panel

Superdrug's online doctor service offers blood testing via in-store phlebotomy at their larger branches. Their panels range from basic health checks to slightly more comprehensive options. The draw is done in-store and samples are sent to an accredited laboratory.

I am honest about where this option sits clinically: the panels are adequate for a first-pass health screen or for clients who are not yet ready to commit to a fuller workup. They do not typically include the functional markers I consider essential — fasting insulin, homocysteine, thyroid antibodies, or sub-fraction lipids are often absent or available only as add-ons.

That said, Superdrug is worth knowing about as an accessible, low-barrier entry point. A client who begins here and sees markers of concern is far more likely to invest in a comprehensive panel subsequently. Sometimes the right first step is the step a client will actually take.

Strengths

  • Very accessible — high street
  • No GP referral required
  • Affordable entry point
  • Walk-in, no long waits

Considerations

  • Limited functional markers
  • Misses insulin, homocysteine, antibodies
  • Not sufficient for full clinical workup
  • Results lack functional interpretation
Best for: Clients at the information-gathering stage who are not yet ready for a comprehensive panel; a first step before committing to a full workup; checking a small number of specific markers between comprehensive panels.

Why Home Phlebotomy Matters Clinically

Access to testing should not be limited by geography or physical capacity

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Older Clients

Travel to a clinic, particularly fasted, is a significant ask for clients in their 70s or 80s. Home draw removes this barrier entirely and ensures the testing actually happens.

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Mobility Limitations

Chronic conditions affecting joints, energy, or stamina — fibromyalgia, ME/CFS, osteoarthritis, MS — make clinic visits effortful. Home draw is a clinical necessity for some, not a luxury.

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Time-Poor Professionals

A fasted morning draw at home, before a full working day, is far easier to schedule than an appointment across town. Removing friction means testing gets done.

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Parents with Young Children

Arranging childcare to attend a clinic while fasted is a genuine logistical challenge. Home draw, with the children present, turns an obstacle into a manageable task.

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Needle Anxiety

A familiar environment reduces anxiety significantly for needle-averse clients. Home draw, with time and comfort, can make testing possible for clients who would otherwise avoid it.

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Rural Clients

Not all of my clients are in Edinburgh. For those in rural Scotland or remote UK locations, there may be no Randox or private clinic within reasonable distance. Home draw solves this.

At a Glance Comparison

Key criteria across all four options

Criteria Randox Signature Regenerus 57 Functional Platinum Bloods & Beyond Superdrug
Marker depth ⭐⭐⭐⭐⭐ 130–180 ⭐⭐⭐ 57 ⭐⭐⭐⭐ 83 Depends on lab ⭐⭐ Basic
Home draw via service via service Core service
All-in client price £598 (test + draw + 2 consults + report) £517 (£317 + £55 + £145) £625 (£425 + £55 + £145) £55 standard draw fee £49–£149
hs-CRP + ESR GP will do free Depends on panel usually
Fasting insulin Depends on panel usually
Homocysteine Depends on panel usually
Immunoglobulins Depends on panel
Full thyroid (incl. antibodies) Depends on panel usually
Sex hormones £95 add-on Depends on panel usually
Omega-3 index Depends on panel
ApoB / Lp(a) Add-on Add-on Depends on lab
Suits elderly / mobility-limited With home draw With home draw Designed for this
TDG programme integration Strong Native Native Via Regenerus Limited

Blood testing within the TDG Programme

Within the TDG Five-Test Programme, I build the cost of blood chemistry into the overall programme fee. This means clients do not pay separately for interpretation — the clinical analysis of their blood chemistry results is included in the practitioner fee, not charged as an additional consultation.

The cost of the test itself (the laboratory fee and any phlebotomy charge) is paid directly to the service provider. Depending on your circumstances, I will recommend the panel that fits the question, and where home draw is the right choice, I will coordinate the Bloods & Beyond arrangement with you directly.

Included
Interpretation within TDG Programme fee
Your choice
Randox, Regenerus, or home draw — based on your circumstances
Coordinated
Home phlebotomy arranged where needed

If you are unsure which option is right for you before booking, the discovery call is the right place to discuss it. I will give you a straight recommendation based on your clinical picture and practical situation.

Not sure which option suits you?

Book a free discovery call. I'll give you a straight recommendation based on your situation — no obligation, no sales pitch.

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